A couple are told by their doctor that they are infertile. The doctor suggests they consider in vitro fertilisation (IVF). Describe what happens during IVF and explain why IVF may be successful for a couple where infertility is caused by the woman's body not producing enough follicle stimulating hormone (FSH).

WJEC A-Level Biology (Wales) — 4.1 Reproductive biology · Describe and Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

1. In IVF, the woman’s ovaries are stimulated with hormones to produce multiple eggs.
2. The eggs are then harvested from the ovaries using a needle.
3. The eggs are mixed with the partner’s sperm in a laboratory dish.
4. Fertilisation occurs outside the body, producing embryos.
5. One or more embryos are transferred into the woman’s uterus, where implantation can occur.

The treatment is successful when the woman’s body does not produce enough follicle‑stimulating hormone (FSH) because the doctor supplies synthetic FSH. This hormone stimulates the ovaries to mature multiple eggs, increasing the chance that at least one egg will fertilise and develop into an embryo that can implant in the uterus.

Examiner tips

  • Use the exact phrase "fertilisation of an egg using sperm outside of the body" to gain the first mark. Show the step of hormone administration to explain why IVF works for low FSH. Include the transfer of embryos into the uterus for the final mark.

Common mistakes

  • Writing that IVF is the same as natural conception. Forgetting to mention the role of synthetic FSH in stimulating egg maturation. Using the word "injection" instead of "administration" of FSH.

Mark scheme (5 marks)

  1. IVF involves fertilisation of an egg using sperm outside of the body
  2. FSH is given to the woman / administered as part of IVF treatment
  3. FSH stimulates the maturation of eggs in the ovary
  4. Mature eggs are collected from the ovary
  5. The fertilised egg(s) / embryo is placed back into the woman's uterus / womb

Key terms in this question

in vitro fertilisation (IVF) · infertility · follicle stimulating hormone (FSH)

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