Explain why a gene can be used as a set of instructions to make a specific protein.
Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).
Genes are sections of DNA found in the nucleus of cells. Each gene codes for a specific protein that the cell needs to function.
Model answer (5 marks)
A gene is a segment of DNA composed of a specific sequence of bases. The order of these bases determines the sequence of codons, each codon being a triplet that specifies a particular amino acid. During transcription the DNA sequence is copied into mRNA, and during translation the ribosome reads the mRNA codons one by one, adding the corresponding amino acids to a growing polypeptide chain. The linear sequence of amino acids then folds into a specific three‑dimensional structure, giving the protein its unique shape and function. Because each gene has a distinct base sequence, it codes for a different amino‑acid sequence and therefore a different protein.
Examiner tips
- Use the word "codon" and "triplet" to show understanding of the genetic code.
- Show the flow: DNA → mRNA → protein, linking sequence to structure.
- Mention that the unique base sequence gives a unique protein.
Common mistakes
- Confusing DNA with RNA or omitting the codon step.
- Failing to state that the amino‑acid sequence determines protein shape.
- Using vague terms like "instructions" without explaining the codon‑amino acid relationship.
Mark scheme (5 marks)
- A gene is a section of DNA / made of bases
- The sequence of bases in a gene codes for the sequence of amino acids in a protein
- Each set of three bases (triplet / codon) codes for a specific amino acid
- The sequence of amino acids determines the structure / shape of the protein
- Different genes have different base sequences, so code for different proteins / each gene codes for a unique protein
Key terms in this question
Related
- All AQA A-Level Biology (7402) revision notes →
- How to answer a "Explain" question →
- Decode the mark scheme abbreviations →
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