Explain how the structure of a DNA nucleotide relates to its function in storing genetic information.

AQA A-Level Biology (7402) — 3.1.5 Nucleic Acids · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

DNA is a polymer made from nucleotide monomers. The sequence of bases in DNA acts as a code for the sequence of amino acids in a protein.

Model answer (5 marks)

1. A DNA nucleotide consists of a deoxyribose sugar, a phosphate group and a nitrogenous base.
2. The four bases are adenine, thymine, cytosine and guanine.
3. The linear sequence of these bases forms a code that determines the sequence of amino acids in a protein.
4. Bases pair specifically – A with T and C with G – which stabilises the double‑stranded structure.
5. The double‑helix with complementary base pairing allows accurate replication of the genetic information during cell division.

Examiner tips

  • Use the exact terms – deoxyribose, phosphate, base; A‑T, C‑G; double helix; replication.
  • Show the link between base sequence and protein coding.
  • Mention complementary base pairing as the basis for accurate copying.
  • Keep each point concise and directly tied to the marks scheme.

Common mistakes

  • Confusing ribose with deoxyribose; writing RNA bases (U) instead of DNA bases.
  • Failing to mention the complementary base pairing or the double‑helix structure.
  • Giving extra information not asked, such as transcription or translation details.

Mark scheme (5 marks)

  1. A DNA nucleotide contains a deoxyribose sugar, a phosphate group, and a (nitrogenous) base
  2. There are four different bases (adenine, thymine, cytosine, guanine) in DNA
  3. The sequence / order of bases acts as a code / carries the genetic information / instructions for making proteins
  4. Bases pair specifically / complementary base pairing (A with T, C with G) holds the two strands together
  5. The double-stranded / double helix structure with complementary base pairing allows accurate copying / replication of genetic information

Key terms in this question

nucleotide

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