Explain how DNA is organised inside a human body cell and how it is used to produce proteins.

AQA A-Level Biology (7402) — 3.4.1 DNA, Genes and Chromosomes · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

DNA is located in the nucleus of a human cell.
The DNA double helix is wrapped around histone proteins to form nucleosomes, which coil and condense to give the structure of chromosomes.
A gene is a defined segment of DNA that contains a sequence of bases.
The order of these bases is read as a code that specifies the sequence of amino acids in a protein.
During transcription the gene is copied to mRNA, which is then translated in the cytoplasm to join amino acids in the correct order, producing a functional protein.

Examiner tips

  • Mention nucleus, histones and chromosomes first. State gene as a DNA segment. Explain base sequence codes for amino acids. Show transcription‑translation flow to protein.
  • common_mistakes
  • :
  • Forgetting to mention the nucleus. Confusing DNA with RNA. Not linking base order to amino acid sequence.

Mark scheme (5 marks)

  1. DNA is found in the nucleus (of a cell)
  2. DNA is wound around proteins / coiled up to form chromosomes
  3. A gene is a section / small part of DNA (that codes for a specific protein)
  4. A gene contains a sequence of bases / the order of bases codes for the amino acid sequence
  5. Amino acids are joined together in the correct order to make a specific protein

Key terms in this question

DNA · protein

Related

More DNA, Genes and Chromosomes questions

▶ Try answering this question with AI marking (free) →