A doctor examines a tissue sample from a patient's liver. She notices that some liver cells are dividing to replace cells that were damaged by disease. Explain how the liver cells produce new cells that are genetically identical to the original liver cell.
Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).
Model answer (5 marks)
The liver cell first replicates its DNA during the S phase of the cell cycle, producing a complete copy of each chromosome so that each chromosome is now a sister chromatid.
The duplicated chromosomes are then segregated during mitosis, ensuring that each daughter nucleus receives a full set of 46 chromosomes.
Mitosis produces two daughter cells from the single parent cell.
Because each daughter cell receives an identical set of chromosomes, the daughter cells are genetically identical to the parent liver cell and to each other.
The duplicated chromosomes are then segregated during mitosis, ensuring that each daughter nucleus receives a full set of 46 chromosomes.
Mitosis produces two daughter cells from the single parent cell.
Because each daughter cell receives an identical set of chromosomes, the daughter cells are genetically identical to the parent liver cell and to each other.
Examiner tips
- Mention DNA replication in S phase, mitosis, and the result of two identical daughter cells.
- Use the exact terms "DNA replication", "mitosis", "46 chromosomes", "genetically identical".
- Show the logical sequence: replication → mitosis → identical daughters.
Common mistakes
- Confusing meiosis with mitosis.
- Failing to state that each daughter cell receives a full set of 46 chromosomes.
- Using vague terms like "copy" instead of "replicate" or "duplicate".
Mark scheme (5 marks)
- The cell replicates / copies its DNA (before division)
- So that each new cell receives a full copy of the genetic information / all 46 chromosomes
- The cell divides by mitosis
- Two daughter cells are produced (from one parent cell)
- The daughter cells are genetically identical to the parent liver cell / to each other, because they contain the same DNA
Key terms in this question
Related
- All AQA A-Level Biology (7402) revision notes →
- How to answer a "Explain" question →
- Decode the mark scheme abbreviations →
More Cell Replication questions
- A student claims that every body cell in a human contains identical genetic info…
- A scientist grows yeast cells in a nutrient solution. After several hours, the n…
- A single fertilised egg cell (zygote) develops into a human embryo containing th…
- A plant cutting is taken from a parent plant and placed in water until roots for…
- A skin cell from a human contains 46 chromosomes. Explain what happens to the ge…
- A muscle cell is damaged during exercise. Describe how mitosis allows the body t…