The brain is divided into distinct regions, each responsible for different functions. Explain why scientists find it difficult to study the brain and map the functions of its different regions.

WJEC A-Level Biology (Wales) — 4.6 The nervous system · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

1. The brain contains billions of neurons, creating an extremely complex network that is difficult to analyse in detail.
2. Functional studies require the brain to be active, so the subject must be alive and the brain must be working during the experiment.
3. Ethical constraints prevent invasive experiments on healthy brains, and patients with brain damage may lack capacity to give informed consent.
4. Most studies are post‑damage; the damaged brain cannot be directly compared with the same individual’s healthy brain, limiting causal inference.
5. Damage rarely produces a single, isolated deficit, making it hard to link a specific problem to a particular region or set of neurons.

Examiner tips

  • Use the exact wording from the mark scheme (e.g., ‘billions of neurons’, ‘must still be working’).
  • Structure answer as numbered points matching the marks.
  • Show understanding of ethical and methodological limits.

Mark scheme (5 marks)

  1. There are billions of neurones in the brain, making it complex to study
  2. The brain must still be working / the patient must be alive in order to study the function of neurones
  3. There are ethical issues with studying the brains of patients with brain damage, as they may not be able to give informed consent
  4. Studies can only be carried out after damage has occurred, so the damaged brain cannot be compared to the patient's healthy brain
  5. Brain damage rarely causes a single problem, so it is difficult to match a specific problem to specific damaged neurones / a specific region

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