Explain why the release of insulin from beta cells in the islets of Langerhans can be described as an example of hormonal communication rather than nervous communication.

OCR A-Level Biology A (H420) — 5.4 Hormonal communication · Explain · 4 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

After a carbohydrate-rich meal, blood glucose concentration rises significantly above the normal range. Specialised cells in the pancreas detect this change and release a chemical messenger directly into the blood.

Model answer (4 marks)

Insulin is secreted directly into the blood, not along a neurone or nerve fibre.

It acts on target cells or organs that are at a distance from the pancreas, rather than at a specific synapse.

Insulin binds to specific complementary receptors on the membranes of target cells, a receptor‑mediated response.

The resulting effect is slower and longer‑lasting than a nervous signal, which uses rapid electrical impulses along neurones.

Examiner tips

  • Use the word ‘secreted directly into the blood’ to show endocrine nature.
  • Mention the distance from release site to target cells.
  • Highlight receptor‑mediated action.
  • Compare speed and duration with nervous communication.

Common mistakes

  • Confusing insulin with a neurotransmitter or saying it acts locally.
  • Failing to mention the blood as the transport medium.
  • Overlooking the receptor‑mediated mechanism.

Mark scheme (4 marks)

  1. Insulin is secreted directly into the blood (not along a neurone/nerve fibre)
  2. Insulin acts on target cells / target organs at a distance from its site of release (rather than at a specific synapse)
  3. Insulin binds to specific complementary receptors on target cell membranes (receptor-mediated response)
  4. The response is slower and longer-lasting compared with nervous communication, which uses electrical impulses along neurones

Key terms in this question

islets of Langerhans · beta cells · hormonal communication

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