Explain why prokaryotic cells, such as bacteria, are different from eukaryotic cells in terms of their subcellular structures.

Eduqas A-Level Biology — 1.2 Cell structure and organisation · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

Prokaryotic cells lack membrane‑bound organelles, so structures such as mitochondria, endoplasmic reticulum and a true nucleus are absent. Their DNA is not enclosed in a nucleus; instead it is a single, circular chromosome that floats freely in the cytoplasm. Prokaryotes also possess plasmids – small, circular DNA molecules that are not usually found in eukaryotes. Consequently, a prokaryotic cell contains only a cell wall, a plasma membrane, cytoplasm and plasmids, whereas a eukaryotic cell has a nucleus and a range of membrane‑bound organelles.

Examiner tips

  • Use the word ‘lack’ to show absence of organelles. Mention the chromosome’s location (cytoplasm). Include plasmids as a distinguishing feature. Keep each point brief to fit the 5‑mark limit.

Common mistakes

  • Confusing the absence of a nucleus with the absence of DNA. Forgetting to mention plasmids. Using vague terms like ‘organelles’ without specifying membrane‑bound ones.

Mark scheme (5 marks)

  1. Prokaryotic cells do not contain membrane-bound organelles (whereas eukaryotic cells do)
  2. Prokaryotic cells do not contain a nucleus / their genetic material is not enclosed in a nucleus
  3. In prokaryotic cells, genetic material (bacterial DNA) moves freely in the cytoplasm
  4. Prokaryotic cells contain plasmids (circular loops of DNA), which are not typically found in eukaryotic cells
  5. Eukaryotic cells (plant and animal cells) contain a nucleus and membrane-bound organelles such as mitochondria, whereas prokaryotic cells only have a cell wall, cell membrane, cytoplasm and plasmids

Key terms in this question

prokaryotic cell · eukaryotic cell

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