Explain why a population of organisms that reproduces only by mitosis is less likely to survive a new disease compared to a population of the same species that reproduces by meiosis.

AQA A-Level Biology (7402) — 3.4.3 Mutation and Meiosis · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

Mitosis produces genetically identical cells, so a population that reproduces only by mitosis is a clone – all individuals have the same genes.
Meiosis, however, creates gametes that combine to form offspring with new combinations of alleles, giving genetic variation.
If a new disease appears, every individual in the clonal population is susceptible because they all share the same susceptible genes.
In the meiotic population, some individuals may carry alleles or mutations that confer resistance to the disease.
Those resistant individuals survive, reproduce and pass the resistance allele on, allowing the population to persist, whereas the clonal population would likely be wiped out.

Examiner tips

  • Use the word ‘genetically identical’ for mitosis and ‘genetic variation’ for meiosis.
  • Show the causal link: identical genes → same susceptibility, variation → possible resistance.
  • Mention survival of resistant individuals and inheritance of the allele.

Common mistakes

  • Confusing mitosis with meiosis or vice‑versa.
  • Failing to explain how variation leads to survival.
  • Using vague terms like ‘different’ instead of ‘genetic variation’.

Mark scheme (5 marks)

  1. Mitosis produces genetically identical cells / clones
  2. So all individuals in the mitosis-only population are genetically identical / have the same genes
  3. Meiosis produces gametes / offspring with genetic variation
  4. Some individuals in the meiosis population may have alleles / mutations that give resistance to the disease
  5. Those resistant individuals survive and reproduce, passing on the resistance allele / the population survives whereas the clonal population would all die

Key terms in this question

meiosis · mitosis

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