Explain how the structure of red blood cells makes them well suited to carrying oxygen around the body.

Edexcel A-Level Biology A: Salters-Nuffield (9BN0) — 1.3 Mass transport in animals · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Red blood cells are specialised cells that transport oxygen from the lungs to respiring tissues. They are found in large numbers in the blood and have several structural adaptations.

Model answer (5 marks)

Red blood cells are biconcave discs, which gives them a very large surface area relative to their volume. This high surface‑area‑to‑volume ratio allows oxygen to diffuse into and out of the cell very quickly.

They contain large amounts of haemoglobin. Haemoglobin binds oxygen in the lungs to form oxyhaemoglobin, which is the form that carries oxygen through the bloodstream.

Red blood cells lack a nucleus and most organelles. The absence of a nucleus frees up space inside the cell for haemoglobin, so each cell can carry more oxygen.

When the blood reaches tissues, oxyhaemoglobin releases its oxygen. The released oxygen then diffuses into the cells, enabling aerobic respiration.

These structural features together make red blood cells highly efficient at transporting oxygen around the body.

Examiner tips

  • Mention the biconcave shape and its effect on surface area/volume ratio; link this to diffusion speed. Include haemoglobin and its oxygen‑binding role. Explain the advantage of no nucleus. Show the release of oxygen at tissues and its importance for respiration.

Common mistakes

  • Forgetting to state that the biconcave shape increases surface area. Failing to mention the lack of a nucleus. Using vague terms like "good shape" without explaining the surface‑area effect.

Mark scheme (5 marks)

  1. Red blood cells have a biconcave disc shape
  2. This increases the surface area to volume ratio, allowing faster diffusion of oxygen into/out of the cell
  3. Red blood cells contain haemoglobin, which binds to oxygen to form oxyhaemoglobin
  4. Red blood cells have no nucleus, leaving more space for haemoglobin / allowing more oxygen to be carried
  5. Oxyhaemoglobin releases oxygen at respiring tissues, allowing cells to carry out aerobic respiration

Key terms in this question

red blood cells

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