Explain how the structure of a mitochondrion allows it to perform its function in cellular respiration.

OCR GCSE Biology A: Gateway Science (J247) — B1 Cell level systems · Explain · 4 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (4 marks)

A mitochondrion has an outer membrane and a highly‑folded inner membrane forming cristae. The inner membrane encloses the matrix, where the Krebs cycle occurs, and contains the electron‑transport chain complexes.

The folds increase surface area, allowing more enzymes and transporters to be embedded, which speeds up the transfer of electrons and the pumping of protons.

Because the inner membrane is impermeable to protons, a proton gradient is created across it. This gradient drives ATP synthase to produce ATP from ADP and inorganic phosphate.

Thus, the double‑membrane structure with extensive cristae provides the necessary surface area and compartmentalisation for efficient oxidative phosphorylation, enabling the mitochondrion to generate the cell’s energy.

Examiner tips

  • Use the term ‘cristae’ and ‘electron‑transport chain’ to show knowledge of structure; link folds to increased surface area; explain proton gradient and ATP synthase; keep answer concise and structured

Common mistakes

  • Confusing the outer membrane with the inner membrane; not mentioning the proton gradient; writing that mitochondria generate energy by photosynthesis

Mark scheme (4 marks)

  1. description of the mitochondrial structure
  2. link between structure and function of mitochondria
  3. role of mitochondria in generating energy
  4. overall explanation of how structure relates to function

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