Explain how the structure of a DNA nucleotide allows DNA to store genetic information and to be replicated accurately.

Edexcel GCSE Biology (1BI0) — 3.3 DNA structure · Explain · 4 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (4 marks)

A DNA nucleotide consists of a phosphate group, a deoxyribose sugar and one of four nitrogenous bases – adenine, thymine, cytosine or guanine.
The linear sequence of these bases along a DNA strand encodes genetic information; the order of bases determines the sequence of amino acids in proteins.
During replication, complementary base pairing occurs: A pairs with T via two hydrogen bonds and C pairs with G via three hydrogen bonds.
Because each strand serves as a template, the complementary base pairing ensures that the new strand receives the exact complementary sequence, allowing accurate copying of the genetic information.

Examiner tips

  • Use the exact terms – nucleotide, phosphate, deoxyribose, adenine, thymine, cytosine, guanine.
  • Show the base‑pairing rule (A‑T, C‑G) and explain its role in replication.
  • Mention that each strand is a template for the new strand.
  • Keep the answer concise – one sentence per point.

Mark scheme (4 marks)

  1. A nucleotide contains one of four chemical bases (A, T, C or G)
  2. The sequence / order of bases along the DNA strand codes for / stores genetic information
  3. Complementary base pairing means A pairs with T and C pairs with G
  4. Complementary base pairing ensures an accurate copy of the base sequence is made during replication / each strand acts as a template

Key terms in this question

DNA

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