DNA is a polymer that forms a double helix structure. Describe the structure of DNA and explain how it is replicated inside a cell.
Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).
Model answer (5 marks)
DNA is a polymer of nucleotides, each consisting of a phosphate, a deoxyribose sugar and a nitrogenous base. Two strands of nucleotides are twisted around each other to form a right‑handed double helix. The bases – adenine, thymine, cytosine and guanine – pair in a complementary way: A with T and C with G, held together by hydrogen bonds.
During replication the double helix is unwound by helicase, separating the two strands. Each single strand then acts as a template for synthesis of a new complementary strand by DNA polymerase, using free nucleotides. The result is two identical DNA molecules, each composed of one original strand and one newly synthesised strand.
During replication the double helix is unwound by helicase, separating the two strands. Each single strand then acts as a template for synthesis of a new complementary strand by DNA polymerase, using free nucleotides. The result is two identical DNA molecules, each composed of one original strand and one newly synthesised strand.
Examiner tips
- Use the term ‘double helix’ and mention complementary base pairing; include helicase and DNA polymerase; state that each new molecule contains one old and one new strand.
- Show the sequence of unwinding, template use and synthesis to cover all points.
Mark scheme (5 marks)
- DNA is made of two strands twisted around each other (forming a double helix)
- DNA contains bases that pair in a complementary way
- The two strands of the double helix unwind / separate
- Each original strand acts as a template for a new complementary strand
- Two identical copies of DNA are produced / each new molecule contains one original strand and one new strand
Key terms in this question
Related
- All Eduqas A-Level Biology revision notes →
- How to answer a "Describe and Explain" question →
- Decode the mark scheme abbreviations →
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