Cell differentiation is an important process in multicellular organisms. Describe what cell differentiation is and explain why, once a cell has differentiated, it cannot produce a cell with a different specialised function.

WJEC A-Level Biology (Wales) — 1.6 Cell division · Describe and Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

Model answer (5 marks)

Cell differentiation is the process by which a cell becomes specialised to perform a particular function, increasing the efficiency of a multicellular organism.

During differentiation the cell alters the expression of genes in its DNA, so that only a specific set of proteins are produced.

Once a cell has differentiated it cannot revert to an unspecialised state because it has lost the ability to express the genes required for other functions.

If a differentiated cell divides, the daughter cells inherit the same specialised gene expression pattern and therefore perform the same function.

Thus a differentiated cell cannot produce a cell with a different specialised function – for example, a heart cell cannot divide to produce a skin cell.

Examiner tips

  • Use the term "specialised" and mention gene expression changes.
  • Explain that differentiation is irreversible and that division keeps the same function.

Common mistakes

  • Confusing differentiation with mitosis or meiosis.
  • Saying a differentiated cell can become any other cell type.
  • Using vague phrases like "change genes" without linking to protein production.

Mark scheme (5 marks)

  1. Cell differentiation is the production of specialised cells (for greater efficiency)
  2. Cells become specialised by altering genes in the cell's DNA
  3. Once differentiated, the cell cannot divide to make an unspecialised cell
  4. When a differentiated cell divides, the daughter cells are already specialised to carry out the same function
  5. Therefore a differentiated cell cannot produce a cell with a different specialised function (e.g. a heart cell cannot divide to produce a skin cell)

Key terms in this question

cell differentiation

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