A student reads that the kidneys filter the blood and then selectively reabsorb useful substances back into the blood, while excreting waste products in urine. Explain how the kidneys carry out excretion, including what is filtered, what is reabsorbed, and what remains in the urine.

OCR A-Level Biology B — Advancing Biology (H422) — 5.6 Excretion · Explain · 5 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

The kidneys are organs of excretion. They remove metabolic waste products from the blood and regulate the water content of the body. Each kidney contains thousands of tiny filtering units.

Model answer (5 marks)

The kidneys filter blood under high hydrostatic pressure to produce a filtrate that contains water, ions, glucose, urea and other small molecules.
1. In the glomerulus, plasma is forced through the filtration membrane, leaving behind a filtrate.
2. In the proximal tubule and other segments of the nephron, useful substances such as glucose, amino acids and most water are selectively reabsorbed back into the bloodstream.
3. Waste products, mainly urea, are not reabsorbed and remain in the filtrate.
4. Urea is produced in the liver from the breakdown of excess amino acids and is therefore a metabolic waste product.
5. The amount of water reabsorbed is regulated by antidiuretic hormone, allowing the kidneys to control the water content of the blood and the concentration of urine.

This explanation covers all five marking points.

Examiner tips

  • Use the sequence: filtration → reabsorption → excretion; mention glomerulus, proximal tubule, urea; state ADH regulation; keep each point brief but complete.
  • Include the origin of urea (liver) to hit the waste‑product point.

Common mistakes

  • Confusing filtration with secretion; not mentioning the glomerulus.
  • Saying all substances are reabsorbed; ignoring urea.
  • Omitting the role of ADH in water reabsorption.

Mark scheme (5 marks)

  1. The kidneys filter the blood (under high pressure) to produce a filtrate
  2. Useful substances such as glucose and water are selectively reabsorbed back into the blood
  3. Urea is not reabsorbed and remains in the filtrate / is excreted in urine
  4. Urea is a waste product formed from the breakdown of excess amino acids (in the liver)
  5. The amount of water reabsorbed is adjusted / regulated to control the water content of the blood

Key terms in this question

excretion · urine

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