A scientist extracts DNA from two different species of organism. They find that in species A, 30% of the bases are adenine. In species B, 40% of the bases are cytosine. Explain what these findings tell us about the base composition of each species' DNA.

Eduqas GCSE Biology — 2.3.1 DNA structure · Explain · 4 marks · View as Markdown

Written & reviewed by James Millett — Biology (Imperial College London), PGCE Science (University of Cambridge).

DNA contains four types of base: adenine (A), thymine (T), cytosine (C) and guanine (G). The bases pair together in a specific way to hold the two strands of the DNA molecule together.

Model answer (4 marks)

In species A, 30 % of the bases are adenine, so by base‑pairing 30 % must be thymine. The remaining 40 % are split equally between cytosine and guanine, giving 20 % each.
In species B, 40 % of the bases are cytosine, so 40 % must be guanine. The remaining 20 % are split equally between adenine and thymine, giving 10 % each.

Examiner tips

  • Use the fact that A pairs with T and C pairs with G; state the percentages explicitly.
  • Show the complementary base for each given base and then calculate the remaining percentages.

Common mistakes

  • Saying that the remaining bases are all the same type instead of splitting them equally.
  • Confusing which base pairs with which (e.g. pairing A with C).

Mark scheme (4 marks)

  1. In species A, 30% of bases are adenine, so 30% must be thymine (because adenine pairs with thymine / complementary base pairing)
  2. In species A, the remaining 40% of bases are split equally between cytosine and guanine (20% each), because cytosine pairs with guanine
  3. In species B, 40% of bases are cytosine, so 40% must be guanine (because cytosine pairs with guanine / complementary base pairing)
  4. In species B, adenine and thymine together make up the remaining 20% of bases (10% each), because adenine pairs with thymine

Key terms in this question

adenine · cytosine

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