# Explain how the process of natural selection can lead to the development of antibiotic resistance in a population of bacteria.

> OCR A-Level Biology A (H420) — 4 Biodiversity, evolution and disease · Explain · 4 marks

## Mark scheme (4 marks)

1. Description of natural selection acting on variation in bacterial population
2. Explanation of how antibiotic use selects for resistant bacteria
3. Description of the outcome of natural selection on bacterial population over time
4. Link to the development of antibiotic resistance as a consequence of natural selection

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