# Describe the process of transgenics, explaining how recombinant DNA is produced and then introduced into a host bacterial cell.

> Pearson Edexcel International GCSE Biology (4BI1) — 5.3 Genetic modification (genetic engineering) · Describe · 4 marks

## Mark scheme (4 marks)

1. Restriction enzymes are used to cut / isolate the desired gene from a chromosome
2. The same restriction enzyme is used to cut open a plasmid (vector), producing compatible / sticky ends
3. Ligase joins / seals the desired gene into the plasmid to produce recombinant DNA
4. The plasmid (vector) is introduced into a host bacterial cell, transferring the recombinant DNA

## Key terms

- [transgenics](https://www.gradenine.co.uk/glossary/transgenics)
- [recombinant DNA](https://www.gradenine.co.uk/glossary/recombinant-dna)

## Related

- [Revision notes for Pearson Edexcel International GCSE Biology (4BI1)](https://www.gradenine.co.uk/learn)
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Source: [GradeNine](https://www.gradenine.co.uk/q/describe-the-process-of-transgenics-explaining-345113eb) · Published by Druglandscape Ltd.